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Motor Unit Number Estimation (MUNE)
by MB Bromberg
Binding: Hardcover, 1 edition, 328 pages
Publisher: Elsevier
List Price: USD $210.00
Weight: 230
Dimension: H: 0.75 x L: 10.4 x W: 0.52 inches
ISBN 10: 044450723X
ISBN 13: 9780444507235
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Book Description:
Hardbound. MUNE is a non invasive, electrophysiologic method to estimate the number of motor neurons innervating a muscle or group of muscles. The ability to quantitatively estimate the number of surviving motor neurons is useful in the following areas: (a) clinically for diagnosis of neuromuscular disorders; (b) as an endpoint measure in clinical drug trials for lower motor neuron disorders; and (c) as a tool to obtain insight into the natural history and pathophysiology of lower motor neuron disorders. Relevant lower motor neuron disorders include amyotrophic lateral sclerosis (ALS), spinal muscular atrophy and Charcot Marie Tooth inherited neuropathies. To date, there has been no formal meeting of investigators working in the field of MUNE. The symposium is designed to: (a) review and discuss the methods, advantages and disadvantages of each MUNE technique; (b) review previous applications of MUNE in research and clinical trials; (c) formulat

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