Since the beginning of Christianity, scripture scholars and theologians have struggled to plumb the true meaning and ramifications of this statement. They have approached it as a way to penetrate into the mysterious depths of who God is and how humans are related to God. The theme of image also has been used by theologians as a key to enter into such questions as how Christ in his divine and human natures functions as God's primary image, how one can grow spiritually to become more like God, and whether women are to be looked upon as equal or subordinate to men. This work presents the Antiochene understandings of how humans are the image of God. Frederick G. McLeod's, S.J., study spans a period of about a hundred years from the middle of the fourth to the middle of the fifth century C.E. He begins with an analysis of the Antiochenes' literal and historical method of interpreting Scripture. He then traces how the leading Fathers of the School of Antioch namely Diodore of Tarsus, Theodore of Mopsuestia, John Chrysostom, Nestorius, and Theodoret applied their scriptural hermeneutical principles to the passages regarding image. Since Theodore's thought on image is the most developed and stimulating of the Antiochenes, his position is primarily stressed. McLeod discusses the ramifications of Theodore's views on image for Christology, especially for understanding prosopon, as well as for soteriology, eschatology, and women's equality. Filled with many new insights, the book highlights the Antiochene writers' unique approach to theology and their contributions to the theology of the Church of the East. No other overview exists in English.