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Endothelial Modulation of Cardiac Function (Endothelial Cell Research)
by Malcolm J Lewis ; Ajay M Shah
Binding: Hardcover, 1 edition, 268 pages
Publisher: CRC
List Price: USD $164.95
Weight: 171
Dimension: H: 0.75 x L: 10.24 x W: 0.49 inches
ISBN 10: 905702120X
ISBN 13: 9789057021206
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Book Description:
Endothelium was originally considered to be an inert lining for the blood vessels, but during the last fifteen years, this view has had to be completely revised. It is now accepted that the endothelium plays an important role in many diverse functions. This volume concentrates on the effect of the endothelium on cardiac function. It has been widely demonstrated that the endothelium exerts a paracrine influence on contraction of adjacent cardiac muscle through the release of several mediators, such as endothelin and nitric oxide. Recent studies also show that the effects of such mediators upon the heart are not limited to contraction alone.Paracrine and autocrine regulation of cardiac function by 'endothelial' mediators is becoming important both physiologically and pathophysiologically. This volume brings the researcher completely up to date with all aspects of endothelial regulation and cardiac function. Acknowledged experts in each field have contributed, making this work indispensabl

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